The integration of geophysical (seismic, seismological, gravity, magnetic, heat flow) data as well as of geological information (stratigraphy, lithology, structure) into consistent models of the basin fill, the crust and the lithosphere is inalienable if we want to derive reasonable boundary conditions concerning the distribution of physical properties and ultimately the allocation of pressure and temperature. Regional 3D structural models per se represent an eclectic base to test different hypotheses. Besides being useful to structural analysis and to calibrate dynamic forward models, they can be the base for different process-oriented studies, as for example the calculation of present-day temperature and pressure conditions or the reconstruction of basin history including the evolution of subsidence, sedimentation, temperature and pressure.